Home

USC-OGP 2-DE database

Two-dimensional polyacrylamide gel electrophoresis database


USC-OGP 2-DE database 
Search by   *
 
 
 
 
 
 
Maps   
 
 


     Select Remote Interfaces
[All Interfaces]
SWISS-2DPAGE
World-2DPAGE Portal
World-2DPAGE Repository

Exclude local DBs
has only effect if a remote
interface is selected
     
Searching in 'USC-OGP 2-DE database' for entry matching: HS90B_HUMAN




USC-OGP 2-DE database:  HS90B_HUMAN


HS90B_HUMAN


General information about the entry
View entry in simple text format
Entry nameHS90B_HUMAN
Primary accession numberP08238
integrated into USC-OGP 2-DE database on January 17, 2017 (release 1)
2D Annotations were last modified onJanuary 17, 2017 (version 1)
General Annotations were last modified on April 5, 2017 (version 2)
Name and origin of the protein
DescriptionRecName: Full=Heat shock protein HSP 90-beta; Short=HSP 90; AltName: Full=Heat shock 84 kDa; Short=HSP 84; Short=HSP84;.
Gene nameName=HSP90AB1
Synonyms=HSP90B, HSPC2, HSPCB
Annotated speciesHomo sapiens (Human) [TaxID: 9606]
TaxonomyEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]   2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein

PLATELET_4-5 {PLATELET 4-5}
Homo sapiens (Human)
PLATELET_4-5
  map experimental info
 
PLATELET_4-5

MAP LOCATIONS:
pI=4.80; Mw=56520



UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10}
Homo sapiens (Human)
UVEAL_MELANOMA_3-10
  map experimental info
 
UVEAL_MELANOMA_3-10

MAP LOCATIONS:
pI=5.20; Mw=104418

Cross-references
UniProtKB/Swiss-ProtP08238; HS90B_HUMAN.



2D PAGE maps for identified proteins
  • How to interpret a protein map
  • You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
  • Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
  • Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed.



External data extracted from UniProtKB/Swiss-Prot
Extracted from UniProtKB/Swiss-Prot, release: 0.0
Entry nameHS90B_HUMAN
Primary accession numberP08238
Secondary accession number(s) B2R5P0 Q5T9W7 Q9NQW0 Q9NTK6
Sequence was last modified on January 23, 2007 (version 4)
Annotations were last modified on March 15, 2017 (version 218)
Name and origin of the protein
DescriptionRecName: Full=Heat shock protein HSP 90-beta; Short=HSP 90; AltName: Full=Heat shock 84 kDa; Short=HSP 84; Short=HSP84;
Gene nameName=HSP90AB1
Synonyms=HSP90B, HSPC2, HSPCB
Encoded onName=HSP90AB1; Synonyms=HSP90B, HSPC2, HSPCB
Keywords3D-structure; Acetylation; ATP-binding; Chaperone; Complete proteome; Cytoplasm; Direct protein sequencing; Glycoprotein; Nucleotide-binding; Phosphoprotein; Polymorphism; Reference proteome; S-nitrosylation; Stress response; Ubl conjugation.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBLM16660; AAA36025.1; -; mRNA
EMBLJ04988; AAA36026.1; -; Genomic_DNA
EMBLAY359878; AAQ63401.1; -; mRNA
EMBLAL136543; CAB66478.1; ALT_FRAME; mRNA
EMBLAK312255; BAG35187.1; -; mRNA
EMBLDQ314872; ABC40731.1; -; Genomic_DNA
EMBLAL139392; CAI20095.1; -; Genomic_DNA
EMBLCH471081; EAX04257.1; -; Genomic_DNA
EMBLBC004928; AAH04928.1; -; mRNA
EMBLBC009206; AAH09206.2; -; mRNA
EMBLBC012807; AAH12807.1; -; mRNA
EMBLBC014485; AAH14485.1; -; mRNA
EMBLBC016753; AAH16753.1; -; mRNA
EMBLBC068474; AAH68474.1; -; mRNA
EMBLAH007358; AAD14062.3; ALT_INIT; Genomic_DNA
EMBLAF275719; AAF82792.1; -; mRNA
CCDSCCDS4909.1; -; .
PIRA29461; HHHU84; .
PIRT46243; T46243; .
RefSeqNP_001258898.1; NM_001271969.1; .
RefSeqNP_001258899.1; NM_001271970.1; .
RefSeqNP_001258900.1; NM_001271971.1; .
RefSeqNP_031381.2; NM_007355.3; .
UniGeneHs.509736; -; .
PDB1QZ2; X-ray; 3.00 A; G/H=720-724
PDB1UYM; X-ray; 2.45 A; A=2-221
PDB2L6J; NMR; -; B=720-724
PDB3FWV; X-ray; 2.20 A; C/D=719-723
PDB3NMQ; X-ray; 2.20 A; A=1-223
PDB3PRY; X-ray; 2.28 A; A/B/C=284-543
PDB3UQ3; X-ray; 2.60 A; B/C=720-724
PDB5FWK; EM; 3.90 A; A/B=1-724
PDB5FWL; EM; 9.00 A; A/B=1-724
PDB5FWM; EM; 8.00 A; A/B=1-724
PDB5FWP; EM; 7.20 A; A/B=1-724
PDBsum1QZ2; -; .
PDBsum1UYM; -; .
PDBsum2L6J; -; .
PDBsum3FWV; -; .
PDBsum3NMQ; -; .
PDBsum3PRY; -; .
PDBsum3UQ3; -; .
PDBsum5FWK; -; .
PDBsum5FWL; -; .
PDBsum5FWM; -; .
PDBsum5FWP; -; .
ProteinModelPortalP08238; -; .
SMRP08238; -; .
BioGrid109558; 314; .
DIPDIP-413N; -; .
IntActP08238; 522; .
MINTMINT-99712; -; .
STRING9606.ENSP00000325875; -; .
BindingDBP08238; -; .
ChEMBLCHEMBL4303; -; .
DrugBankDB05134; CNF1010; .
DrugBankDB02424; Geldanamycin; .
DrugBankDB03758; Radicicol; .
DrugBankDB06070; SNX-5422; .
GuidetoPHARMACOLOGY2907; -; .
iPTMnetP08238; -; .
PhosphoSitePlusP08238; -; .
SwissPalmP08238; -; .
DMDM17865718; -; .
OGPP08238; -; .
EPDP08238; -; .
MaxQBP08238; -; .
PaxDbP08238; -; .
PeptideAtlasP08238; -; .
PRIDEP08238; -; .
TopDownProteomicsP08238; -; .
DNASU3326; -; .
EnsemblENST00000353801; ENSP00000325875; ENSG00000096384; .
EnsemblENST00000371554; ENSP00000360609; ENSG00000096384; .
EnsemblENST00000371646; ENSP00000360709; ENSG00000096384; .
EnsemblENST00000620073; ENSP00000481908; ENSG00000096384; .
GeneID3326; -; .
KEGGhsa:3326; -; .
UCSCuc003oxa.3; human; .
CTD3326; -; .
DisGeNET3326; -; .
GeneCardsHSP90AB1; -; .
H-InvDBHIX0031498; -; .
H-InvDBHIX0057380; -; .
HGNCHGNC:5258; HSP90AB1; .
HPACAB005230; -; .
HPAHPA055729; -; .
MIM140572; gene; .
neXtProtNX_P08238; -; .
OpenTargetsENSG00000096384; -; .
PharmGKBPA29524; -; .
eggNOGKOG0019; Eukaryota; .
eggNOGKOG0020; Eukaryota; .
eggNOGCOG0326; LUCA; .
GeneTreeENSGT00840000129758; -; .
HOGENOMHOG000031988; -; .
HOVERGENHBG007374; -; .
InParanoidP08238; -; .
KOK04079; -; .
OMAAFANDIC; -; .
OrthoDBEOG091G0270; -; .
PhylomeDBP08238; -; .
TreeFamTF300686; -; .
ReactomeR-HSA-2029482; Regulation of actin dynamics for phagocytic cup formation; .
ReactomeR-HSA-3371511; HSF1 activation; .
ReactomeR-HSA-3371568; Attenuation phase; .
ReactomeR-HSA-3371571; HSF1-dependent transactivation; .
ReactomeR-HSA-399954; Sema3A PAK dependent Axon repulsion; .
ReactomeR-HSA-5336415; Uptake and function of diphtheria toxin; .
ReactomeR-HSA-6798695; Neutrophil degranulation; .
ReactomeR-HSA-844456; The NLRP3 inflammasome; .
ReactomeR-HSA-8852276; The role of GTSE1 in G2/M progression after G2 checkpoint; .
ReactomeR-HSA-8937144; Aryl hydrocarbon receptor signalling; .
SIGNORP08238; -; .
ChiTaRSHSP90AB1; human; .
EvolutionaryTraceP08238; -; .
GeneWikiHSP90AB1; -; .
GenomeRNAi3326; -; .
PROPR:P08238; -; .
ProteomesUP000005640; Chromosome 6; .
BgeeENSG00000096384; -; .
CleanExHS_HSP90AB1; -; .
ExpressionAtlasP08238; baseline and differential; .
GenevisibleP08238; HS; .
GOGO:0016324; C:apical plasma membrane; IEA:Ensembl; .
GOGO:0034751; C:aryl hydrocarbon receptor complex; IDA:UniProtKB; .
GOGO:0016323; C:basolateral plasma membrane; IEA:Ensembl; .
GOGO:0031526; C:brush border membrane; IEA:Ensembl; .
GOGO:0009986; C:cell surface; IEA:Ensembl; .
GOGO:0005737; C:cytoplasm; IDA:UniProtKB; .
GOGO:0005829; C:cytosol; IDA:HPA; .
GOGO:0070062; C:extracellular exosome; IDA:UniProtKB; .
GOGO:0005576; C:extracellular region; TAS:Reactome; .
GOGO:1904813; C:ficolin-1-rich granule lumen; TAS:Reactome; .
GOGO:0016234; C:inclusion body; IEA:Ensembl; .
GOGO:0005765; C:lysosomal membrane; IEA:Ensembl; .
GOGO:0042470; C:melanosome; IEA:UniProtKB-SubCell; .
GOGO:0016020; C:membrane; IDA:UniProtKB; .
GOGO:0005739; C:mitochondrion; IDA:UniProtKB; .
GOGO:0005654; C:nucleoplasm; TAS:Reactome; .
GOGO:0005634; C:nucleus; IDA:UniProtKB; .
GOGO:1990917; C:ooplasm; IEA:Ensembl; .
GOGO:0034774; C:secretory granule lumen; TAS:Reactome; .
GOGO:1990913; C:sperm head plasma membrane; IEA:Ensembl; .
GOGO:0005524; F:ATP binding; IEA:UniProtKB-KW; .
GOGO:0045296; F:cadherin binding; IDA:BHF-UCL; .
GOGO:0002135; F:CTP binding; IEA:Ensembl; .
GOGO:0032564; F:dATP binding; IEA:Ensembl; .
GOGO:0070182; F:DNA polymerase binding; IPI:BHF-UCL; .
GOGO:0003725; F:double-stranded RNA binding; IDA:MGI; .
GOGO:0008144; F:drug binding; IEA:Ensembl; .
GOGO:0005525; F:GTP binding; IEA:Ensembl; .
GOGO:0031072; F:heat shock protein binding; IPI:UniProtKB; .
GOGO:0042826; F:histone deacetylase binding; IPI:BHF-UCL; .
GOGO:1990226; F:histone methyltransferase binding; IPI:UniProtKB; .
GOGO:0019900; F:kinase binding; IPI:UniProtKB; .
GOGO:0023026; F:MHC class II protein complex binding; IDA:UniProtKB; .
GOGO:0030235; F:nitric-oxide synthase regulator activity; ISS:UniProtKB; .
GOGO:0046983; F:protein dimerization activity; IDA:UniProtKB; .
GOGO:0019887; F:protein kinase regulator activity; IEA:Ensembl; .
GOGO:0003723; F:RNA binding; IDA:UniProtKB; .
GOGO:0030911; F:TPR domain binding; ISS:UniProtKB; .
GOGO:0002134; F:UTP binding; IEA:Ensembl; .
GOGO:0035690; P:cellular response to drug; IEA:Ensembl; .
GOGO:0071353; P:cellular response to interleukin-4; IEA:Ensembl; .
GOGO:0071407; P:cellular response to organic cyclic compound; IEA:Ensembl; .
GOGO:0038096; P:Fc-gamma receptor signaling pathway involved in phagocytosis; TAS:Reactome; .
GOGO:1903660; P:negative regulation of complement-dependent cytotoxicity; IEA:Ensembl; .
GOGO:0043524; P:negative regulation of neuron apoptotic process; IEA:Ensembl; .
GOGO:0032435; P:negative regulation of proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB; .
GOGO:0043312; P:neutrophil degranulation; TAS:Reactome; .
GOGO:0001890; P:placenta development; IEA:Ensembl; .
GOGO:0045597; P:positive regulation of cell differentiation; IMP:UniProtKB; .
GOGO:0045793; P:positive regulation of cell size; IEA:Ensembl; .
GOGO:0045429; P:positive regulation of nitric oxide biosynthetic process; ISS:UniProtKB; .
GOGO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IDA:UniProtKB; .
GOGO:0032092; P:positive regulation of protein binding; IEA:Ensembl; .
GOGO:0033160; P:positive regulation of protein import into nucleus; translocation; IEA:Ensembl
GOGO:2000010; P:positive regulation of protein localization to cell surface; IDA:UniProtKB; .
GOGO:0071902; P:positive regulation of protein serine/threonine kinase activity; IEA:Ensembl; .
GOGO:0051973; P:positive regulation of telomerase activity; IDA:BHF-UCL; .
GOGO:0030511; P:positive regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB; .
GOGO:0006457; P:protein folding; IEA:InterPro; .
GOGO:0050821; P:protein stabilization; TAS:Reactome; .
GOGO:1900034; P:regulation of cellular response to heat; TAS:Reactome; .
GOGO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; IMP:MGI; .
GOGO:0031396; P:regulation of protein ubiquitination; IDA:BHF-UCL; .
GOGO:0060338; P:regulation of type I interferon-mediated signaling pathway; IMP:MGI; .
GOGO:0042220; P:response to cocaine; IEA:Ensembl; .
GOGO:0009651; P:response to salt stress; IEA:Ensembl; .
GOGO:0006986; P:response to unfolded protein; NAS:UniProtKB; .
GOGO:0097435; P:supramolecular fiber organization; IMP:CACAO; .
GOGO:1905323; P:telomerase holoenzyme complex assembly; IDA:BHF-UCL; .
GOGO:0007004; P:telomere maintenance via telomerase; IDA:BHF-UCL; .
GOGO:0019062; P:virion attachment to host cell; IMP:CACAO; .
GOGO:0006805; P:xenobiotic metabolic process; TAS:Reactome; .
Gene3D3.30.565.10; -; 2; .
HAMAPMF_00505; HSP90; 1; .
InterProIPR003594; HATPase_C; .
InterProIPR019805; Heat_shock_protein_90_CS; .
InterProIPR001404; Hsp90_fam; .
InterProIPR020575; Hsp90_N; .
InterProIPR020568; Ribosomal_S5_D2-typ_fold; .
PANTHERPTHR11528; PTHR11528; 1; .
PfamPF02518; HATPase_c; 1; .
PfamPF00183; HSP90; 1; .
PIRSFPIRSF002583; Hsp90; 1; .
PRINTSPR00775; HEATSHOCK90; .
SMARTSM00387; HATPase_c; 1; .
SUPFAMSSF54211; SSF54211; 1; .
SUPFAMSSF55874; SSF55874; 1; .
PROSITEPS00298; HSP90; 1; .



USC-OGP 2-DE database image


Gateways to other related servers


Database constructed and maintained by Angel Garcia, using the Make2D-DB II package (ver. 3.10.2) from the World-2DPAGE Constellation of the ExPASy web server

[Home]